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KMID : 0032220140260020241
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Annals of Dermatology
2014 Volume.26 No. 2 p.241 ~ p.245
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Photodynamic Therapy for Bowen’s Disease of the Vulva Area
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Kang Hong-Kyu
Yun Jeong-Hwan
Son Young-Min
Roh Joo-Young
Lee Jong-Rok
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Abstract
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Bowen’s disease is a squamous cell carcinoma in situ and has the potential to progress to a squamous cell carcinoma. The authors treated two female patients (a 39-year-old and a 41-year-old) with Bowen’s disease in the vulva area using topical photodynamic therapy (PDT), involving the use of 5-aminolaevulinic acid and a light- emitting diode device. The light was administered at an intensity of 80 mW/cm2 for a dose of 120 J/cm2 biweekly for 6 cycles. The 39-year-old patient showed excellent clinical improvement, but the other patient achieved only a partial response. Even though one patient underwent a total excision 1 year later due to recurrence, both patients were satisfied with the cosmetic outcomes of this therapy and the partial improvement over time. The common side effect of PDT was a stinging sensation. PDT provides a relatively effective and useful alternative treatment for Bowen’s disease in the vulva area. (Ann Dermatol 26(2) 241∼245, 2014)
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KEYWORD
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Bowen’s disease, Photochemotherapy, Vulva area
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